Eye Diseases, Hereditary
Showing 1 - 25 of >10,000
Natural History of PRPF31 Mutation-Associated Retinal Dystrophy
Recruiting
- Retinitis Pigmentosa
- +4 more
-
San Francisco, California
- +4 more
Oct 5, 2022
Leber Congenital Amaurosis 10, Inherited Retinal Dystrophies, Eye Diseases, Hereditary Trial in United States (EDIT-101)
Active, not recruiting
- Leber Congenital Amaurosis 10
- +6 more
-
Miami, Florida
- +4 more
Dec 2, 2022
Natural History Study of CEP290-Related Retinal Degeneration
Completed
- Blindness
- +7 more
-
Miami, Florida
- +6 more
May 18, 2022
Retinitis Pigmentosa, Retinitis, Retinal Diseases Trial in Puerto Rico, United States (Gene Therapy Product-vMCO-010, Sham
Active, not recruiting
- Retinitis Pigmentosa
- +6 more
- Gene Therapy Product-vMCO-010
- Sham Injection
-
Beverly Hills, California
- +6 more
Jul 13, 2022
Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind Trial in Dallas, Madison, London (QR-421a, Sham-procedure)
Active, not recruiting
- Retinitis Pigmentosa
- +7 more
- QR-421a
- Sham-procedure
-
Dallas, Texas
- +2 more
Apr 21, 2022
Graves Ophthalmopathy, Graves Disease, Thyroid-associated Ophthalmopathy Trial in Guangzhou (Doxycycline hyclate, Placebo)
Recruiting
- Graves Ophthalmopathy
- +8 more
- Doxycycline hyclate
- Placebo
-
Guangzhou, Guangdong, ChinaZhongshan Ophthalmic Center
Nov 16, 2021
Leber Congenital Amaurosis 10, Blindness, Leber Congenital Amaurosis Trial in Iowa City, Philadelphia, Ghent (QR-110)
Active, not recruiting
- Leber Congenital Amaurosis 10
- +9 more
-
Iowa City, Iowa
- +2 more
Feb 8, 2022
PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
Recruiting
- Retinal Degeneration
- +2 more
-
San Francisco, California
- +7 more
Jan 12, 2022
Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind Trial in Worldwide (Ultevursen, Sham-procedure)
Recruiting
- Retinitis Pigmentosa
- +7 more
- Ultevursen
- Sham-procedure
-
San Diego, California
- +14 more
Jul 29, 2022
Stickler Syndrome Trial in Paris (Encircling scleral buckle surgical procedure)
Not yet recruiting
- Stickler Syndrome
- Encircling scleral buckle surgical procedure
-
Paris, FranceHôpital Cochin
Apr 6, 2022
Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind Trial in Canada, France, United States (QR-421a, Sham-procedure (dose
Completed
- Retinitis Pigmentosa
- +7 more
- QR-421a
- Sham-procedure (dose cohort 1&2 only)
-
Boston, Massachusetts
- +6 more
Apr 19, 2022
Leber Congenital Amaurosis 10, Blindness, Leber Congenital Amaurosis Trial in Worldwide (sepofarsen, Sham)
Active, not recruiting
- Leber Congenital Amaurosis 10
- +9 more
- sepofarsen
- Sham
-
Iowa City, Iowa
- +13 more
Mar 2, 2022
Ophthalmological Disorder, Corneal Dystrophy, Treatment Trial in Alicante (Implantation, Lipoaspiration)
Recruiting
- Ophthalmological Disorder
- +4 more
- Implantation
- Lipoaspiration
-
Alicante, SpainJorge L. Alio
Oct 18, 2022
Leber Hereditary Optic Neuropathy Trial in Worldwide (GS010, Sham)
Completed
- Leber Hereditary Optic Neuropathy
- GS010
- Sham
-
Pasadena, California
- +6 more
Jul 25, 2022
Leber Hereditary Optic Neuropathy Trial in Worldwide (GS010, Placebo)
Active, not recruiting
- Leber Hereditary Optic Neuropathy
- GS010
- Placebo
-
Pasadena, California
- +12 more
Aug 2, 2022
Leber's Hereditary Optic Neuropathy Trial in Pasadena (elamipretide (MTP-131) 1% topical ophthalmic solution, Vehicle topical
Completed
- Leber's Hereditary Optic Neuropathy
- elamipretide (MTP-131) 1% topical ophthalmic solution
- Vehicle topical ophthalmic solution
-
Pasadena, CaliforniaDoheny Eye Center
Nov 29, 2021
Fuchs Endothelial Corneal Dystrophy, FECD3, Corneal Diseases Trial in London (QR-504a)
Withdrawn
- Fuchs Endothelial Corneal Dystrophy
- +4 more
-
London, United KingdomMoorfields Eye Hospital, NIHR Clinical Research Facility
May 5, 2022
Retinitis Pigmentosa, Leber's Hereditary Optic Neuropathy, Stargardt Disease Trial in Paris (Dynamic pupillometry sessions)
Completed
- Retinitis Pigmentosa
- +2 more
- Dynamic pupillometry sessions
-
Paris, FranceCentre Hospitalier National D'Ophtalùmologie des Quinze-Vingts
May 28, 2021
Strabismus, Congenital Cranial Dysinnervation Disorders, and
Recruiting
- Congenital Fibrosis of Extraocular Muscles
- +25 more
-
Boston, MassachusettsBoston Children's Hospital
Sep 23, 2022
Leber's Hereditary Optic Neuropathy Trial in Miami (injection of scAAV2-P1ND4v2 1.18x10e9 vg (Low),, injection of scAAV2-P1ND4v2
Active, not recruiting
- Leber's Hereditary Optic Neuropathy
- injection of scAAV2-P1ND4v2 1.18x10e9 vg (Low),
- +3 more
-
Miami, FloridaBascom Palmer Eye Institute, University of Miami
Jul 1, 2021
Disease and Visual Disability on Quality of Life and Loss of
Recruiting
- Leber's Hereditary Optic Neuropathy (LHON)
-
Orléans, FranceArgo Sante
Sep 22, 2022
Leber Hereditary Optic Neuropathy (LHON) Trial (NFS-02 Injection)
Not yet recruiting
- Leber Hereditary Optic Neuropathy (LHON)
- NFS-02 Injection
- (no location specified)
Apr 6, 2023
Leber Hereditary Optic Neuropathy Trial in Worldwide (Patient-reported outcomes (PROs))
Completed
- Leber Hereditary Optic Neuropathy
- Patient-reported outcomes (PROs)
-
Pasadena, California
- +10 more
Feb 3, 2021
Trial
Not yet recruiting
- Leber Hereditary Optic Neuropathy (LHON)
- NR082 Injection
- Injection needle
- (no location specified)
Jan 30, 2023